| Статус: | Not yet recruiting |
| Фаза: | не указано |
| Начало: | 1 марта 2024 г. |
| Окончание: | 31 января 2029 г. |
| Описание: | Identification of risk factors that cause a high probability of an unfavorable outcome in the postoperative period is an urgent problem. The creation of national databases (registries) makes it possible to maximally cover a certain patient population by identifying its characteristic risk predictors. As literature data show, existing registries differ in the criteria for inclusion in the study, in the characteristics of the populations studied, and there is often no common view on the classification of postoperative outcomes. Goal of a study is a creation of a Russian national calculator for the risk of postoperative complications and mortality. Two-level observational retrospective-prospective study was planned. Setting: National multicenter study of surgical inpatients. Patients: Adult patients undergoing elective and emergency surgery. Types of interventions: in obstetrics, in gynecology, on the breast, in urology and kidneys, in endocrine surgery, in maxillofacial surgery, in orthopedics and traumatology, on the lower floor of the abdominal cavity, on the liver and biliary tract, on the upper floor of the abdominal cavity cavities, in thoracic surgery, in vascular surgery, in neurosurgery, in cardiac surgery, in other areas (with mandatory specification). The study was organized by the Federation of Anesthesiologists and Reanimatologists of Russia. Primary (30-day mortality, 30-day complications) and secondary (hospital mortality, hospital complications, length of stay in anesthesiology, resuscitation and intensive care departments, length of hospital stay, multiple organ failure (2 or more points on the SOFA scale (Sequential)) Organ Failure Assessment), 90-day mortality, 90-day complications, intensive care after-effects syndrome, readmission, 1-year mortality) outcomes were determined. The required sample size and statistical analysis methods are described. The planned duration of the study is 2024-2028. |
| смотреть на ClinicalTrials.gov |
| Статус: | Completed |
| Фаза: | N/A |
| Начало: | 12 марта 2022 г. |
| Окончание: | 31 августа 2024 г. |
| Описание: | The investigators are suggtesting that lower goals of systolic blood pressure after intravenous thrombolysis may reduce the risk of hemorrhagic complications and improve functional outcomes after acute ischemic stroke. |
| смотреть на ClinicalTrials.gov |
| Статус: | Recruiting |
| Фаза: | не указано |
| Начало: | 1 июля 2019 г. |
| Окончание: | 28 февраля 2025 г. |
| Описание: | Study is conducted to assess the prevalence and structure of comorbidity among patients undergoing abdominal surgery and produce the stratification of the risk of postoperative complications by identifying independent predictors for its development. |
| смотреть на ClinicalTrials.gov |
| Статус: | Completed |
| Фаза: | N/A |
| Начало: | 1 августа 2015 г. |
| Окончание: | 1 февраля 2016 г. |
| Описание: | This study evaluates the influence of alveolar recruitment maneuver, protocolized liberation from respiratory support and monitoring of Integrated Pulmonary Index on the duration of the mechanical ventilation and the number of pulmonary complications in the early postoperative period after cardiac surgery. |
| смотреть на ClinicalTrials.gov |
| Статус: | Completed |
| Фаза: | N/A |
| Начало: | 1 марта 2015 г. |
| Окончание: | 1 ноября 2015 г. |
| Описание: | The major combined interventions are between challenging and high-risk aspects of current cardiosurgical practice. The results of operation may be hampered by unexpected anatomic and technical features influencing the surgical approach as well as cardiopulmonary bypass (CPB), anesthesia, and respiratory support. Plasma lactate concentration is a routine clinical indicator of the tissue oxygen shortage, and is routinely monitored in virtually all in-risk surgical and ICU patients. However, the discrete measurement of these values among with other biochemical values has a major drawback and continuous measurement can be beneficial. The aim of our study is to assess the clinical usefulness and rationale for routine use of continuous monitoring of lactate in high-risk combined/complex cardiac surgery. |
| смотреть на ClinicalTrials.gov |
| Статус: | Unknown status |
| Фаза: | N/A |
| Начало: | 1 января 2015 г. |
| Окончание: | 1 января 2021 г. |
| Описание: | Objective: To assess the predictive value of dynamic tests and parameters for evaluation of fluid responsiveness after off-pump coronary artery bypass grafting (OPCAB). After arrival to ICU, all patients received positive end-expiratory pressure test (PEEP-test), mini-fluid challenge test (mFCT) and standard fluid challenge test (sFCT) to assess fluid responsiveness. In addition, investigators measured pulse pressure variation using two monitoring systems (PPVPiCCO and PPVNK), stroke volume variation (SVV), heart-lung interaction index (HLI) and plethysmogram variability index (PVI) before and after sFCT. |
| смотреть на ClinicalTrials.gov |
| Статус: | Completed |
| Фаза: | N/A |
| Начало: | 1 июня 2014 г. |
| Окончание: | 1 июня 2014 г. |
| Описание: | The main goal of our study is to assess the accuracy and reproducibility of continuous beat-to-beat cardiac output (CO) measurement using pulse wave transit time in patients undergoing off-pump coronary artery bypass grafting. |
| смотреть на ClinicalTrials.gov |
| Статус: | Completed |
| Фаза: | N/A |
| Начало: | 1 октября 2012 г. |
| Окончание: | 1 августа 2016 г. |
| Описание: | Abdominal surgery commonly requires perioperative relaxation and therefore controlled mechanical ventilation. However, respiratory support can be associated with minor, yet clinically significant changes in blood gas content. The inadvertent hyperoxia (excessively high oxygen) and/or hypocapnia (excessively low carbon dioxide) can result in transient changes in cerebral blood flow and cognitive impair. |
| смотреть на ClinicalTrials.gov |
| Статус: | Unknown status |
| Фаза: | не указано |
| Начало: | 1 октября 2011 г. |
| Окончание: | 1 марта 2013 г. |
| Описание: | The aim of our study was to evaluate the reliability of uncalibrated cardiac index monitoring based on arterial waveform analysis in patients undergoing off-pump coronary artery bypass grafting. |
| смотреть на ClinicalTrials.gov |
| Статус: | Unknown status |
| Фаза: | не указано |
| Начало: | 1 октября 2011 г. |
| Окончание: | 1 марта 2013 г. |
| Описание: | The aim of our study was to evaluate the reliability of uncalibrated cardiac index monitoring based on arterial waveform analysis in patients undergoing off-pump coronary artery bypass grafting. |
| смотреть на ClinicalTrials.gov |